Nuclear factor kappa-B

A protein complex that controls transcription of DNA, cytokine production and cell survival which is found in almost all animal cell types and is involved in cellular responses to stimuli. Most longevity researchers agree that, though NFkB is important for survival, in general people are healthiest when there is not too chronic an over-expression of this molecule, as does naturally occur in most people as they age. Many herbs reduce the expression of NFkB, most notably Gynostemma, Curcumin, Astragalus and Goji. Actually, most tonic herbs reduce expression of NFkB.